Can I sync my Galaxy Nexus using USB?
The Galaxy Nexus only has USB MTP mode, which doubleTwist was not designed for as it expects USB Mass Storage (MSC) mode.We are currently working on adding USB MTP support to doubleTwist.
In the meantime, you can use AirSync to sync with USB MTP only devices such as the Galaxy Nexus and Android 3 tablets.
Here are some quickstart guides to AirSync.
Quickstart For Windows
Quickstart for Mac